Acetaminophen and Pets
Find out if Acetaminophen is toxic to dogs and cats.
Think your pet ate something toxic?
Call ASPCA Animal Poison Control Center: (888) 426-4435 or view emergency guide
Acetaminophen (Paracetamol, Tylenol)
Acetaminophen is a common human pain reliever and fever reducer, but it is not safe for pets. Dogs can develop liver injury and methemoglobinemia at higher doses, while cats are extremely sensitive—even small amounts can be fatal.
Cats lack the liver enzymes needed to safely break down acetaminophen. Signs of poisoning can appear quickly and include vomiting, lethargy, difficulty breathing, blue or brown gums, facial or paw swelling, and collapse. In dogs, toxic effects may include vomiting, loss of appetite, abdominal pain, jaundice, and dark urine.
Never give acetaminophen to a dog or cat unless specifically directed by a veterinarian. Keep all medications, including single-dose packets and pills left in bags or pockets, out of reach of pets.
If you suspect your pet has swallowed acetaminophen, contact your veterinarian or a pet poison control center immediately. Quick treatment, which may include decontamination, supportive care, and antidotes, can improve the outcome.
Is Acetaminophen Toxic to Dogs?
Acetaminophen can cause liver injury, gastrointestinal upset, and—at high doses—methemoglobinemia in dogs; do not give without veterinary guidance.
Is Acetaminophen Toxic to Cats?
Even small doses can be life-threatening in cats, causing methemoglobinemia, hemolysis, facial/paw edema, and acute liver failure.
Active Ingredients
- acetaminophen
Common Brand Names
- Tylenol
- Panadol
- Mapap
- FeverAll
- Ofirmev
Dosage Form
tabletcapletgelcapliquid suspensionsuppositoryintravenous injection
Common Uses
- human pain relief
- fever reduction
Toxic Ingredients
- acetaminophen
Symptoms to Watch For
- vomiting
- lethargy
- loss of appetite
- difficulty breathing
- cyanosis (blue/grey/brown gums)
- facial or paw swelling
- jaundice
- dark urine
- collapse
What If My Pet Was Exposed to Acetaminophen?
Call your veterinarian or a pet poison control hotline immediately. Do not induce vomiting unless instructed. Bring the medication bottle/label and estimate the amount ingested. Transport your pet for emergency evaluation as soon as possible.
Sources
Vet's Note
PetPilot provides general information for educational purposes. While we reference authoritative veterinary organizations, this page has not been individually reviewed by a veterinarian for your specific pet. Individual animals may react differently based on age, weight, breed, health conditions, and amount consumed. Always consult your veterinarian or a poison control center for personalized advice, especially if your pet is ill, injured, pregnant, nursing, or on medication.