Skip to main content
Amitriptyline

Amitriptyline and Pets

Find out if Amitriptyline is toxic to dogs and cats.

Dogs: Toxic
Cats: Toxic

Think your pet ate something toxic?

Call ASPCA Animal Poison Control Center: (888) 426-4435 or view emergency guide

Amitriptyline is highly toxic to both dogs and cats. Even a small number of human tablets can cause severe neurological and cardiovascular effects, including seizures, abnormal heart rhythms, and death. Keep all prescription medications in a secure cabinet away from pets.

Pets are most often exposed by chewing through pill bottles, eating dropped tablets, or being accidentally given a human medication. Signs of poisoning can appear within minutes to a few hours and may worsen quickly.

If you suspect your pet ate amitriptyline, treat it as an emergency. Contact your veterinarian or an animal poison control center immediately, and bring the medication bottle with you.

To prevent poisoning, store all antidepressants out of reach, pick up dropped pills right away, and never give your pet a human medication without veterinary guidance.

Is Amitriptyline Toxic to Dogs?

Even small amounts can cause life-threatening agitation, seizures, and cardiac arrhythmias.

Is Amitriptyline Toxic to Cats?

Extremely dangerous; cats can develop severe neurological signs, hyperexcitability, and arrhythmias.

Active Ingredients

  • amitriptyline

Common Brand Names

  • Elavil

Dosage Form

tabletcompounded oral liquid

Common Uses

  • depression
  • anxiety
  • neuropathic pain
  • behavioral disorders

Toxic Ingredients

  • amitriptyline

Symptoms to Watch For

  • vomiting
  • diarrhea
  • lethargy
  • hyperexcitability
  • agitation
  • tremors
  • seizures
  • abnormal heart rhythm
  • hypotension
  • hyperthermia
  • dilated pupils
  • respiratory distress

What If My Pet Was Exposed to Amitriptyline?

Seek emergency veterinary care immediately. Bring the medication bottle and estimate the quantity and time of ingestion. Do not induce vomiting unless directed by a veterinarian or poison control hotline.

Sources

Vet's Note

PetPilot provides general information for educational purposes. While we reference authoritative veterinary organizations, this page has not been individually reviewed by a veterinarian for your specific pet. Individual animals may react differently based on age, weight, breed, health conditions, and amount consumed. Always consult your veterinarian or a poison control center for personalized advice, especially if your pet is ill, injured, pregnant, nursing, or on medication.

Medical DisclaimerThe content on this page is not a substitute for professional veterinary diagnosis, treatment, or emergency care. If you suspect your pet has been exposed to something harmful, contact your veterinarian or call ASPCA Poison Control or Pet Poison Helpline immediately.